"These signaling functions suggest that BHB might itself regulate inflammation and gene expression, with implications for health and longevity. Aberrant inflammasome activity is associated with a variety of age-related diseases (Goldberg and Dixit, 2015), while moderate inhibition of histone deacetylases is associated with enhanced longevity in invertebrates (Woods and Rogina, 2016) as well as amelioration of cognitive decline (Penney and Tsai, 2014) and cardiac dysfunction (Morales et al., 2016) in mice."
maybe related:
cell: "Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice" ( 5 September 2017 )
http://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)3...
BHB == ketone body beta-hydroxybutyrate
"These signaling functions suggest that BHB might itself regulate inflammation and gene expression, with implications for health and longevity. Aberrant inflammasome activity is associated with a variety of age-related diseases (Goldberg and Dixit, 2015), while moderate inhibition of histone deacetylases is associated with enhanced longevity in invertebrates (Woods and Rogina, 2016) as well as amelioration of cognitive decline (Penney and Tsai, 2014) and cardiac dysfunction (Morales et al., 2016) in mice."