Yes, you should think about your domain and requirements, and the technical tradeoffs, before picking a DB technology. Don't just run with RDBMS b/c it has better theoretical modeling capabilities, your customers don't care about that.
For enterprise stuff with relatively low traffic and high amounts of complex ad-hoc queries, RDBMS is without a doubt the best choice. If you have high traffic web services with strict availability and latency requirements, I would seriously consider avoiding RDBMS's as they tend to be difficult to operate and scale with those requirements, and they let you easily do terrible things in that context (e.g. locking behavior, txid exhaustion, etc.).
For enterprise stuff with relatively low traffic and high amounts of complex ad-hoc queries, RDBMS is without a doubt the best choice. If you have high traffic web services with strict availability and latency requirements, I would seriously consider avoiding RDBMS's as they tend to be difficult to operate and scale with those requirements, and they let you easily do terrible things in that context (e.g. locking behavior, txid exhaustion, etc.).