So, people do this a lot and frequently make mistakes. For example, when you knock out a gene, you also damage any overlapping genes (yes, genes can overlap). most studies don't pay attention to the damage they do to overlapping genes.
The underlying physical model for how gene products interact to make phenotypes ends up being so hopelessly complex and latent that most conclusions in this area end up being "sufficient, but not necessary" instead of "necessary, but not sufficient"
The underlying physical model for how gene products interact to make phenotypes ends up being so hopelessly complex and latent that most conclusions in this area end up being "sufficient, but not necessary" instead of "necessary, but not sufficient"