This does explain a lot of the difference in development, especially in very poor countries. And this isn’t just a result of “old”, traditional colonialism, but imperialism in the form of meddling in their internal politics. Guatemala is a great example, having had its democracy destroyed by Allen Dulles and his CIA in the 1950s. But you can also take a more recent example like the 2009 coup in Honduras, backed by Hillary Clinton.
The DC establishment will do anything to prevent an isolationist from taking power-- that would begin the rollback of the sprawling empire from which they derive their largess. Trump was terrible domestically, and he was only isolationist in some areas (certainly less damaging overall than the Karen). He also appointed some usual suspects from the Deep State who are extremely interventionist (John Bolton, ffs).