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[flagged] Forget Psychedelics. Everyone's Microdosing Ozempic Now (hollywoodreporter.com)
22 points by adrian_mrd 9 months ago | hide | past | favorite | 17 comments


Since this is a throwaway story/ad I will put an entertaining anecdote.

Last year I was working as a janitor at McDonald's to comply with my release from federal prison after my computer hacking case.

During this time I started dieting a simple set of changes. I basically just ate twice a day, once was tuna with something and another was salad. No exceptions.

I dropped the weight slowly but very surely. From 280 to 220 very easily.

At this restaurant we're two women who were overweight. Both of them went and took a trip to Mexico to have an invasive stomach surgery. One of them lost over 100lbs if you include the weight they made her lose before she could do the surgery.

However, one of the surgeries was botched somehow and the woman went into a coma for a month. They were attempting to pull the plug on her, get donated organs, and talking with her family about the needless suffering she would endure if they sent her to a long term care facility.

She woke up out of that coma a month later and has been making a recovery since.

It sparked a conversation with my wife and we both independently came up with the same ideas. We want to be given a chance to recover, but we would want each other to move on and not become an excessive burden beyond a year. Plus we have no idea what kind of existence we would be subjecting someone to.


Interestingly, some research indicates around ¼ of coma patients may be conscious. Patients even held 2-way conversations using an fMRI scanner!

https://www.sciencefocus.com/the-human-body/comas-conscious-...


> Last year I was working as a janitor at McDonald's to comply with my release from federal prison after my computer hacking case.

Uhh, please expand on that…


I love how this movie starts ...


Why is this clickbait on the front page?


What an impressive advertisement.

I'm wondering if this is just what rich people are being sold instead of coffee and a good night's sleep now, or is the experience separate from that? Anyone have first hand experience?


Wonder where will they build a wall now to stop this drug.


On this subject: I remember a few years ago there was a fad in SV for microdosing psychadelics. What happened to that?


they still do - an extremely prominent criminal in the US is a noted SV ketamine addict, though I am pretty confident he's also abusing amphetamines on the other side to stay up all night tweeting white supremacy.


Is Ozempic popular in SV / among the tech crowd? I was under the impression that it is a weight loss drug.


It is a weight loss drug primarily. There are other effects observed and it seems to be something people are experimenting with. I'm not fully convinced this drug is fully understood.


That may be true, but this isn't exactly a new drug overall. It has been available as a diabetes treatment since about 2005. So we should have some longer-term data on the topic.


It’s a weight loss drug primarily by reducing appetite, but I believe there are also metabolic effects being discovered, and slowing of the metabolism increases longevity.


There's a lot of stuff in there that sounds like pseudoscience. Insulin-resistant brain? Are you sure?


The article is from thehollywoodreporter, so it is expected to not go into great detail. There is real research around these lines and links between Alzheimers and insulin resistance. I'm not in the field to really be able to vet, but it seems more than pseudoscience. Here is some more research on the topic: https://pmc.ncbi.nlm.nih.gov/articles/PMC2769828/


Great, another global medical experiment.

At least this one is voluntary.

You don't increase profits by solving problems, you increase them by causing addiction/worse problems down the line.


There was a commercial on during the Super Bowl last night that started with talking about how broken the healthcare and food system is in the US. “This system wasn’t built to help us. It was built to keep us sick and stuck” was one of the lines.

Then the reveal was that it’s an ad for Hims & Hers selling glp-1 for weight loss. Not “let’s fix any of the system that is making everyone so sick”, but “here take a drug because we know we don’t have the will to overcome our dystopian system”.

This isn’t me being against glp-1, but something about that ad really made me feel gross.




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